The PSIpred protein structure prediction server - Liam
نویسندگان
چکیده
Article : Predicting bacterial genes by ORPHEUS Grigory Kolesov(1), Andrey Mironov(2), Mikhail Gelfand(3), Hans-Werner Mewes(1), and Dmitrij Frishman(1) (1) Munich Information Center for Protein Sequences (MIPS) of the German National Center for Health and Environment (GSF) (2) Laboratory of Mathematical Methods, National Center for Biotechnology Information, Moscow (3) Institute of Protein Research, Russian Academy of Sciences, Pushchino, Russia.
منابع مشابه
The PSIPRED protein structure prediction server
SUMMARY The PSIPRED protein structure prediction server allows users to submit a protein sequence, perform a prediction of their choice and receive the results of the prediction both textually via e-mail and graphically via the web. The user may select one of three prediction methods to apply to their sequence: PSIPRED, a highly accurate secondary structure prediction method; MEMSAT 2, a new ve...
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The method starts by constructing a set of subsequences from the query sequence, each subsequence representing a hypothesis for a possible protein domain. This is done by scanning against the InterPro database and using hits as domain hypotheses [1]. Additional hypotheses are constructed using a secondary structure prediction from PSIPRED [2]. Segments of predicted loops are used as potential d...
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MOTIVATION A new method that uses support vector machines (SVMs) to predict protein secondary structure is described and evaluated. The study is designed to develop a reliable prediction method using an alternative technique and to investigate the applicability of SVMs to this type of bioinformatics problem. METHODS Binary SVMs are trained to discriminate between two structural classes. The b...
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